Treatment challenges for lichen planopilaris

Lichen Planus    American Skin Association

In general, lichen planus is not a harmful or fatal disease. Other tests may be needed if your doctor suspects you have any of the several variations of lichen planus, such as the type that affects the esophagus, genitals, ears or mouth. In DLE, inflammation is not restricted to surrounding hairs, and the affected skin can become telangiectetic. However, there are no long-term studies in the literature that shed light on the natural course of the disease.

Scope of recovery is very little and relapse is a common occurrence. Baibergenova A, Walsh S. Light therapy phototherapy may help clear up lichen planus affecting the skin.

Therapeutic management of classic lichen planopilaris: a systematic review

The presence of skin lesions is not constant and may wax and wane over time. Lichen Planopilaris is a form of lichen planus that mostly affects women in young adulthood. Among those treated with an immunosuppressant, the 3 patients treated with mycophenolate had no change in the condition; 4 of the 10 patients treated with methotrexate achieved partial remission, 4 were unchanged, and 2 experienced a worsening of the condition.

The symptoms of Lichen Planopilaris differ from individual to individual. Sexual dysfunction can become a long-term complication. Lichen Planus What is lichen planus? About one-third of patients treated with doxycycline actually showed a worsening of symptoms.

Pickert A. Besides this comparative analysis, there are other studies on the use of antimalarials in LPP.

The inflammatory process tends to cease spontaneously. Mycop henolate mofetil highest level of evidence: The biopsy specimen must be taken from an active lesion that displays perifollicular erythema and perifollicular scaling. Request an Appointment at Mayo Clinic. Int J Prev Med.

Lichen Planopilaris - Symptoms, Causes, Treatment & Prevention RichFeel

Rare Diseases Dermatology. Talk with your doctor before trying an alternative treatment for lichen planus. I have also been explained in the language I understand that the results of each therapy may vary from person to person depending upon individual body composition, health status, metabolism and other factors including diet and lifestyle and as such results of the therapy cannot be guaranteed and the lack of results will not be construed as deficiency of service.

Lichen Planopilaris may cause permanent hair loss and scarring due to primary Cicatricial Alopecia. The most common areas are the inner wrists, the forearms and the ankles. Evidence from a retrospective chart analysis of an open-label trial including 16 LPP recalcitrant instances treated with mycophenolate mofetil 0.

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Hair transplant in scarring alopecia. In addition, it can affect other parts of the body, such as the nails, scalp, vulva, vagina and penis. You can learn about our use of cookies by reading our Privacy Policy.

Hunt N, McHale S. The lesions also show scaling towards the periphery. No conflicts of interest were declared. When Lichen Planus affects the scalp and causes bald patches, it is called Lichen Planopilaris. This disease can affect any individual all over the world, regardless of the race, skin color and culture. Some medications cause this condition. This disorder has been known to occur after contact with certain chemicals, such as those used to develop color photographs.